Article
Common sequence variants in the major histocompatibility complex region associate with cerebral ventricular size in schizophrenia.
Biological psychiatry - 1 Oct 2011
Agartz Ingrid, Brown Andrew Anand, Rimol Lars M, Hartberg Cecilie B, Dale Anders M, Melle Ingrid, Djurovic Srdjan, Andreassen Ole A
Abstract excerpt
BACKGROUND: Because of evidence from genetic linkage and genome-wide association studies, as well as suggested involvement of infection, the major histocompatibility complex (MHC) region on chromosome 6p21.3-22.1 has been implicated in the development of schizophrenia. METHODS: Here, we investigated how gene variants across the MHC region are associated with brain structure in a large ethnically homogenous sample...
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