Article
Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese.
Biological psychiatry - 1 Oct 2010
Li Tao, Li Zhiqiang, Chen Peng, Zhao Qian, Wang Ti, Huang Ke, Li Junyan, Li You, Liu Jie, Zeng Zhen, Feng Guoyin, He Lin, Shi Yongyong
Abstract excerpt
BACKGROUND: Schizophrenia is a complex major psychiatric disorder affecting ∼1% of the world population. Recently, in a genome-wide association study and a follow-up in Caucasians, Stefansson et al. examined 7662 schizophrenic cases and 29053 normal control subjects and reported seven common single nucleotide polymorphisms (SNPs) that were significantly (>10(-8)) associated with schizophrenia. METHODS: To...
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