Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Contribution from MHC-Mediated Risk in Schizophrenia Can Reflect a More Ethnic-Specific Genetic and Comorbid Background.

Cells - 30 Aug 2022

Srinivas Lekshmy, Vellichirammal Neetha N, Nair Indu V, Nair Chandrasekharan M, Banerjee Moinak

Abstract excerpt

The immune system seems to play a significant role in the development of schizophrenia. This becomes more evident with the emerging role of MHC complex and cytokines in schizophrenia. In the recent past, several GWAS have implied that the 6p21 region was associated with schizophrenia. However, the majority of these studies were performed in European populations. Considering tremendous variations in this region...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Ethnicity
Share to Histocompatibility Antigens Class I

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Histocompatibility Antigens Class II

Share to Polymorphism, Single Nucleotide

Share to Proteins

Share to Psoriasis

Share to Schizophrenia

Source

Open in PubMed Open full text

Identifiers

PMID: 36078103
DOI: 10.3390/cells11172695
PMCID: PMC9454640

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Contribution from MHC-Mediated Risk in Schizophrenia Can Reflect a More Ethnic-Specific Genetic and Comorbid Background.PMID 36078103Read ↗

HLA associations in schizophrenia: are we re-discovering the wheel?Semantic proximity Read ↗

Genome-wide association studies: findings at the major histocompatibility complex locus in psychosis.Semantic proximity Read ↗

Common susceptibility variants are shared between schizophrenia and psoriasis in the Han Chinese population.Semantic proximity Read ↗

Population-dependent contribution of the major histocompatibility complex region to schizophrenia susceptibility.Semantic proximity Read ↗

Genetic Evidence for a Neuroimmune Model of Schizophrenia.Semantic proximity Read ↗

The highly pleiotropic gene SLC39A8 as an opportunity to gain insight into the molecular pathogenesis of schizophrenia.Semantic proximity Read ↗

Association study between genetic variants and the risk of schizophrenia in the Chinese population based on GWAS-implicated 6p21.3-23.1 human genome region: a case-control study.Semantic proximity Read ↗

Variation in the major histocompatibility complex [MHC] gene family in schizophrenia: associations and functional implications.Semantic proximity Read ↗

Common variants on chromosome 6p22.1 are associated with schizophrenia.Semantic proximity Read ↗

The impact of HLA-G 3' UTR variants and sHLA-G on risk and clinical correlates of schizophrenia.Semantic proximity Read ↗

Cross-disorder analysis of schizophrenia and 19 immune diseases reveals genetic correlationSemantic proximity Read ↗

No association observed between schizophrenia and non-HLA coeliac disease genes: integration with the initial MYO9B association with coeliac disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.