Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia.

Biological psychiatry - 15 Oct 2012

Abstract excerpt

BACKGROUND: We performed a genome-wide association study (GWAS) to identify common risk variants for schizophrenia. METHODS: The discovery scan included 1606 patients and 1794 controls from Ireland, using 6,212,339 directly genotyped or imputed single nucleotide polymorphisms (SNPs). A subset of this sample (270 cases and 860 controls) was subsequently included in the Psychiatric GWAS Consortium-schizophrenia...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged, 80 and over
Share to Calcium Channels, T-Type
Share to Databases, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genome-Wide Association Study

Share to HLA-C Antigens

Share to Ireland

Share to Schizophrenia

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 22883433
DOI: 10.1016/j.biopsych.2012.05.035
PMCID: PMC3529467

Genes

TCF4
VRK2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genome-wide association study implicates HLA-C*01:02 as a risk factor at the major histocompatibility complex locus in schizophrenia.PMID 22883433Read ↗

Genome-wide association studies: findings at the major histocompatibility complex locus in psychosis.Semantic proximity Read ↗

Common variants at VRK2 and TCF4 conferring risk of schizophrenia.Semantic proximity Read ↗

Common variants conferring risk of schizophrenia.Semantic proximity Read ↗

Common variants in major histocompatibility complex region and TCF4 gene are significantly associated with schizophrenia in Han Chinese.Semantic proximity Read ↗

Population-dependent contribution of the major histocompatibility complex region to schizophrenia susceptibility.Semantic proximity Read ↗

[Search for risk genes in schizophrenia].Semantic proximity Read ↗

Genome-wide association study in a Swedish population yields support for greater CNV and MHC involvement in schizophrenia compared with bipolar disorder.Semantic proximity Read ↗

Common variants on 2p16.1, 6p22.1 and 10q24.32 are associated with schizophrenia in Han Chinese population.Semantic proximity Read ↗

Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC.Semantic proximity Read ↗

Genetic variation in the Major Histocompatibility Complex and association with depressionSemantic proximity Read ↗

Search for schizophrenia susceptibility variants at the HLA-DRB1 locus among a British population.Semantic proximity Read ↗

HLA typing using genome wide data reveals susceptibility types for infections in a psychiatric disease enriched sample.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.