Article
Impact of functional germline variants and a deletion polymorphism in APOBEC3A and APOBEC3B on breast cancer risk and survival in a Swedish study population.
Journal of cancer research and clinical oncology - 1 Jan 2016
Göhler Stella, Da Silva Filho Miguel Inacio, Johansson Robert, Enquist-Olsson Kerstin, Henriksson Roger, Hemminki Kari, Lenner Per, Försti Asta
Abstract excerpt
PURPOSE: The C → T mutation signature caused by APOBEC family members contributes to the development of breast cancer (BC). Also overexpression of APOBEC3B and a ~29.5-kb deletion polymorphism between APOBEC3A and APOBEC3B have been associated with increased BC risk. METHODS: We investigated in a population-based study, with 782 Swedish BC cases and 1559 controls, associations between potentially functional...
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