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Article

Current guidelines for BRCA testing of breast cancer patients are insufficient to detect all mutation carriers.

BMC cancer - 21 Jun 2017

Grindedal Eli Marie, Heramb Cecilie, Karsrud Inga, Ariansen Sarah Louise, Mæhle Lovise, Undlien Dag Erik, Norum Jan, Schlichting Ellen

Abstract excerpt

BACKGROUND: Identification of BRCA mutations in breast cancer (BC) patients influences treatment and survival and may be of importance for their relatives. Testing is often restricted to women fulfilling high-risk criteria. However, there is limited knowledge of the sensitivity of such a strategy, and of the clinical aspects of BC caused by BRCA mutations in less selected BC cohorts. The aim of this report was to...

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Identifiers

PMID: 28637432
DOI: 10.1186/s12885-017-3422-2
PMCID: PMC5480128

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