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Article

Functional germline variants in driver genes of breast cancer.

Cancer causes & control : CCC - 1 Apr 2017

Göhler Stella, Da Silva Filho Miguel Inacio, Johansson Robert, Enquist-Olsson Kerstin, Henriksson Roger, Hemminki Kari, Lenner Per, Försti Asta

Abstract excerpt

PURPOSE: Germline mutations in tumour suppressor genes cause various cancers. These genes are also somatically mutated in sporadic tumours. We hypothesized that there may also be cancer-related germline variants in the genes commonly mutated in sporadic breast tumours. METHODS: After excluding the well-characterized breast cancer (BC) genes, we screened 15 novel genes consistently classified as BC driver genes in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28238063
DOI: 10.1007/s10552-017-0849-3

Genes

RUNX1
TTN
ATR
TBX3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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