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Article

Opposed expression of IKKα: loss in keratinizing carcinomas and gain in non-keratinizing carcinomas.

Oncotarget - 22 Sept 2015

Xiao Desheng, Jia Jiantao, Shi Ying, Fu Chunyan, Chen Ling, Jiang Yiqun, Zhou Li, Liu Shuang, Tao Yongguang

Abstract excerpt

The functional role of IKKα in vivo is pretty complicated, largely due to its diverse functions through cell autonomous and non-autonomous manners. In addition, most of the studies on IKKα were derived from animal models, whether these findings hold true in human tumors remain unclear. Here we ex...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 26317791
DOI: 10.18632/oncotarget.4548
PMCID: PMC4694847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-26317791-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

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Opposed expression of IKKα: loss in keratinizing carcinomas and gain in non-keratinizing carcinomas.PMID 26317791Read ↗

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Cells lacking IKKα show nuclear cyclin D1 overexpression and a neoplastic phenotype: role of IKKα as a tumor suppressor.Semantic proximity Read ↗

Keratin expression in human tissues and neoplasms.Semantic proximity Read ↗

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IKKβ overexpression leads to pathologic lesions in stratified epithelia and exocrine glands and to tumoral transformation of oral epithelia.Semantic proximity Read ↗

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Epigenetic Inactivation of IκB Kinase-α in Oral Carcinomas and Tumor ProgressionSemantic proximity Read ↗

IKKα mediates UVB-induced cell apoptosis by regulating p53 pathway activationSemantic proximity Read ↗

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