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IKKα mediates UVB-induced cell apoptosis by regulating p53 pathway activation

12 Oct 2021

Abstract excerpt

Exposure to ultraviolet B (UVB) has been demonstrated to induce DNA damage as well as angiogenesis-related photo-damages, which are implicated in a variety of medical problems, including sunburn, photo-aging and skin cancers. However, the molecular mechanism related to UVB-induced photo-injuries remained fully elucidated. Here we revealed that one of the catalytic subunits of the IKK complex, IKKα, played a...

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PMID: 34649141
DOI: 10.1016/j.ecoenv.2021.112892

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