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Article

Distinct Actin and Lipid Binding Sites in Ysc84 Are Required during Early Stages of Yeast Endocytosis.

PloS one - 1 Jan 2015

Urbanek Agnieszka N, Allwood Ellen G, Smith Adam P, Booth Wesley I, Ayscough Kathryn R

Abstract excerpt

During endocytosis in S. cerevisiae, actin polymerization is proposed to provide the driving force for invagination against the effects of turgor pressure. In previous studies, Ysc84 was demonstrated to bind actin through a conserved N-terminal domain. However, full length Ysc84 could only bind actin when its C-terminal SH3 domain also bound to the yeast WASP homologue Las17. Live cell-imaging has revealed that...

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Identifiers

PMID: 26312755
DOI: 10.1371/journal.pone.0136732
PMCID: PMC4552428

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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