Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility.

The Journal of cell biology - 10 Oct 2005

Chang Fanny S, Han Gil-Soo, Carman George M, Blumer Kendall J

Abstract excerpt

Endosomes in yeast have been hypothesized to move through the cytoplasm by the momentum gained after actin polymerization has driven endosome abscision from the plasma membrane. Alternatively, after abscission, ongoing actin polymerization on endosomes could power transport. Here, we tested these hypotheses by showing that the Arp2/3 complex activation domain (WCA) of Las17 (Wiskott-Aldrich syndrome protein...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Actins
Share to Biological Transport
Share to Endosomes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Movement

Share to Receptors, Mating Factor

Share to Saccharomyces cerevisiae Proteins

Share to Structural Homology, Protein

Share to Wiskott-Aldrich Syndrome Protein

Source

Open in PubMed Open full text

Identifiers

PMID: 16216926
DOI: 10.1083/jcb.200501086
PMCID: PMC2171216

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A WASp-binding type II phosphatidylinositol 4-kinase required for actin polymerization-driven endosome motility.PMID 16216926Read ↗

Distinct Actin and Lipid Binding Sites in Ysc84 Are Required during Early Stages of Yeast Endocytosis.Semantic proximity Read ↗

SLAC, a complex between Sla1 and Las17, regulates actin polymerization during clathrin-mediated endocytosis.Semantic proximity Read ↗

Phosphorylation of the WH2 domain in yeast Las17/WASP regulates G-actin binding and protein function during endocytosis.Semantic proximity Read ↗

Cellular functions of WASP family proteins at a glanceSemantic proximity Read ↗

Endocytic internalization in budding yeast requires coordinated actin nucleation and myosin motor activity.Semantic proximity Read ↗

The Saccharomyces cerevisiae homologue of human Wiskott-Aldrich syndrome protein Las17p interacts with the Arp2/3 complex.Semantic proximity Read ↗

The F-BAR protein Syp1 negatively regulates WASp-Arp2/3 complex activity during endocytic patch formation.Semantic proximity Read ↗

Direct comparison of clathrin-mediated endocytosis in budding and fission yeast reveals conserved and evolvable featuresSemantic proximity Read ↗

Remodeling of organelle-bound actin is required for yeast vacuole fusion.Semantic proximity Read ↗

Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complexSemantic proximity Read ↗

WIPI1 promotes fission of endosomal transport carriers and formation of autophagosomes through distinct mechanismsSemantic proximity Read ↗

The yeast dynamin-like protein Vps1:vps1 mutations perturb the internalization and the motility of endocytic vesicles and endosomes via disorganization of the actin cytoskeleton.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.