Article
Interaction of Sla2p's ANTH domain with PtdIns(4,5)P2 is important for actin-dependent endocytic internalization.
Molecular biology of the cell - 1 Feb 2005
Sun Yidi, Kaksonen Marko, Madden David T, Schekman Randy, Drubin David G
Abstract excerpt
A variety of studies have implicated the lipid PtdIns(4,5)P2 in endocytic internalization, but how this lipid mediates its effects is not known. The AP180 N-terminal homology (ANTH) domain is a PtdIns(4,5)P2-binding module found in several proteins that participate in receptor-mediated endocytosi...
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