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Article

SLAC, a complex between Sla1 and Las17, regulates actin polymerization during clathrin-mediated endocytosis.

Molecular biology of the cell - 1 Nov 2012

Feliciano Daniel, Di Pietro Santiago M

Abstract excerpt

During clathrin-mediated endocytosis, branched actin polymerization nucleated by the Arp2/3 complex provides force needed to drive vesicle internalization. Las17 (yeast WASp) is the strongest activator of the Arp2/3 complex in yeast cells; it is not autoinhibited and arrives to endocytic sites 20...

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Identifiers

PMID: 22973053
DOI: 10.1091/mbc.E11-12-1022
PMCID: PMC3484103

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-22973053-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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SLAC, a complex between Sla1 and Las17, regulates actin polymerization during clathrin-mediated endocytosis.PMID 22973053Read ↗

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