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Article

Association of the functional BCL-2 rs2279115 genetic variant and small cell lung cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Feb 2016

Yang Xinyu, Gao Feng, Ma Fei, Ren Yanli, Chen Hongwei, Liang Xue, Han Sichong, Xiong Xiangyu, Pan Wenting, Zhou Changchun, Zhou Liqing, Yang Ming

Abstract excerpt

As a well-known oncogene, B cell lymphoma-2 (BCL-2) can promote cancer cell survival through preventing their apoptosis. Several functional BCL-2 single nucleotide polymorphisms (SNPs), such as rs2279115, rs1801018, and rs1564483, have been identified and might contribute to cancer susceptibility. However, the involvement of these SNPs in small cell lung cancer (SCLC) was still unclear. As a result, we...

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Source

Identifiers

PMID: 26311051
DOI: 10.1007/s13277-015-3934-9

Genes

BCL2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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