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Article

Functional BCL-2 regulatory genetic variants contribute to susceptibility of esophageal squamous cell carcinoma.

Scientific reports - 1 Jul 2015

Pan Wenting, Yang Jinyun, Wei Jinyu, Chen Hongwei, Ge Yunxia, Zhang Jingfeng, Wang Zhiqiong, Zhou Changchun, Yuan Qipeng, Zhou Liqing, Yang Ming

Abstract excerpt

B-cell lymphoma-2 (BCL-2) prevents apoptosis and its overexpression could promote cancer cell survival. Multiple functional BCL-2 genetic polymorphisms, such as rs2279115, rs1801018 and rs1564483, have been identified previously and might be involved in cancer development through deregulating BCL-2 expression. Therefore, we examined associations between these three polymorphisms and esophageal squamous cell...

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Source

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Identifiers

PMID: 26132559
DOI: 10.1038/srep11833
PMCID: PMC4487241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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