Association of genetic polymorphism of BCL-2 (rs2279115) with susceptibility to HCV-related hepatocellular carcinoma.

doi:10.1007/s12026-020-09143-7

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Article

Association of genetic polymorphism of BCL-2 (rs2279115) with susceptibility to HCV-related hepatocellular carcinoma.

Immunologic research - 1 Aug 2020

Ahmed Hanan S, Wahab Essam A, Elhady Hoda A, Elgerby Manal M

Abstract excerpt

Hepatitis C virus (HCV) infection is the main risk factor for chronic hepatitis (CHC), liver cirrhosis, and hepatocellular carcinoma (HCC). B cell lymphoma-2 (BCL-2) prevents apoptosis, and its overexpression could promote cancer cell survival. The purpose of this study is to evaluate the association of Bcl-2 gene polymorphism (rs2279115) and HCV-related HCC susceptibility. Two hundred and seventy individuals...

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PMID: 32623689
DOI: 10.1007/s12026-020-09143-7

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