Association of genetic polymorphism of BCL-2 (rs2279115) with susceptibility to HCV-related hepatocellular carcinoma.

doi:10.1007/s12026-020-09143-7

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Article

Association of genetic polymorphism of BCL-2 (rs2279115) with susceptibility to HCV-related hepatocellular carcinoma.

Immunologic research - 1 Aug 2020

Ahmed Hanan S, Wahab Essam A, Elhady Hoda A, Elgerby Manal M

Abstract excerpt

Hepatitis C virus (HCV) infection is the main risk factor for chronic hepatitis (CHC), liver cirrhosis, and hepatocellular carcinoma (HCC). B cell lymphoma-2 (BCL-2) prevents apoptosis, and its overexpression could promote cancer cell survival. The purpose of this study is to evaluate the associa...

Topics

Adult
Aged
Alleles
Carcinogenesis
Carcinoma, Hepatocellular
Case-Control Studies
Female
Genetic Predisposition to Disease
Hepacivirus
Hepatitis C, Chronic
Humans
Liver Neoplasms
Male
Middle Aged
Polymorphism, Single Nucleotide
Proto-Oncogene Proteins c-bcl-2

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Open in PubMed

Identifiers

PMID: 32623689
DOI: 10.1007/s12026-020-09143-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-32623689-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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