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Article

Intronic single-nucleotide polymorphisms in Bcl-2 are associated with chronic obstructive pulmonary disease severity.

Respirology (Carlton, Vic.) - 1 Jan 2007

Sata Makoto, Takabatake Noriaki, Inoue Sumito, Shibata Yoko, Abe Shuichi, Machiya Jun-ichi, Wada Toshihiro, Ji Guijin, Kido Takashi, Matsuura Tadashi, Muramatsu Masa-aki, Kubota Isao

Abstract excerpt

BACKGROUND AND OBJECTIVE: COPD is a multifactorial disease influenced by genetic and environmental factors, and gene-by-environmental interactions. There is considerable variability in the degree of airflow obstruction, moreover only 10-15% of chronic smokers develop COPD. These observations indicate that additional risk factors, possibly genetic, contribute to not only the susceptibility to COPD but also the...

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Identifiers

PMID: 17207023
DOI: 10.1111/j.1440-1843.2006.00959.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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