Article
A genome-wide association and gene-environment interaction study for serum triglycerides levels in a healthy Chinese male population.
Human molecular genetics - 1 Apr 2012
Tan Aihua, Sun Jielin, Xia Ning, Qin Xue, Hu Yanling, Zhang Shijun, Tao Sha, Gao Yong, Yang Xiaobo, Zhang Haiying, Kim Seong-Tae, Peng Tao, Lin Xiaoling, Li Li, Mo Linjian, Liang Zhengjia, Shi Deyi, Huang Zhang, Huang Xianghua, Liu Ming, Ding Qiang, Trent Jeffrey M, Zheng S Lilly, Mo Zengnan, Xu Jianfeng
Abstract excerpt
Triglyceride (TG) is a complex phenotype influenced by both genetic and environmental factors. Recent genome-wide association studies (GWAS) have identified genes or loci affecting lipid levels; however, such studies in Chinese populations are limited. A two-stage GWAS were conducted to identify genetic variants that were associated with TG in a Chinese population of 3495 men. Gene-environment interactions on...
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