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Article

Whole-genome pathway analysis on 132,497 individuals identifies novel gene-sets associated with body mass index.

PloS one - 1 Jan 2014

Simonson Matthew A, McQueen Matthew B, Keller Matthew C

Abstract excerpt

Whole genome pathway analysis is a powerful tool for the exploration of the combined effects of gene-sets within biological pathways. This study applied Interval Based Enrichment Analysis (INRICH) to perform whole-genome pathway analysis of body-mass index (BMI). We used a discovery set composed of summary statistics from a meta-analysis of 123,865 subjects performed by the GIANT Consortium, and an independent...

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Identifiers

PMID: 24497910
DOI: 10.1371/journal.pone.0078546
PMCID: PMC3908858

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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