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Article

Ensemble and single-molecule biophysical characterization of D17.4 DNA aptamer-IgE interactions.

Biochimica et biophysica acta - 1 Jan 2016

Poongavanam Mohan-Vivekanandan, Kisley Lydia, Kourentzi Katerina, Landes Christy F, Willson Richard C

Abstract excerpt

BACKGROUND: The IgE-binding DNA aptamer 17.4 is known to inhibit the interaction of IgE with the high-affinity IgE Fc receptor FcεRI. While this and other aptamers have been widely used and studied, there has been relatively little investigation of the kinetics and energetics of their interactions with their targets, by either single-molecule or ensemble methods. METHODS: The dissociation kinetics of the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26307469
DOI: 10.1016/j.bbapap.2015.08.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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