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Article

Association of HLA-DRB1 genetic variants with the persistence of atopic dermatitis.

Human immunology - 1 Aug 2015

Margolis David J, Mitra Nandita, Kim Brian, Gupta Jayanta, Hoffstad Ole J, Papadopoulos Maryte, Wubbenhorst Bradley, Nathanson Katherine L, Duke Jamie L, Monos Dimitri S, Kamoun Malek

Abstract excerpt

Atopic dermatitis (AD) is a waxing and waning illness of childhood that is likely caused by interactions between an altered skin barrier and immune dysregulation. The goal of our study was to evaluate the association of DRB1 genetic variants and the persistence of AD using whole exome sequencing and high resolution typing. DRB1 was interrogated based on previous reports that utilized high throughput techniques....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 26307177
DOI: 10.1016/j.humimm.2015.08.003
PMCID: PMC4593755

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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