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Article

Filaggrin-2 variation is associated with more persistent atopic dermatitis in African American subjects.

The Journal of allergy and clinical immunology - 1 Mar 2014

Margolis David J, Gupta Jayanta, Apter Andrea J, Ganguly Tapan, Hoffstad Ole, Papadopoulos Maryte, Rebbeck Tim R, Mitra Nandita

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) is a common skin disease characterized by recurrent episodes of itching. Genetic variation associated with the persistence of AD has not been described for African American subjects. OBJECTIVE: We sought to evaluate genetic variation of filaggrin-2 (FLG2) in African American subjects with AD. METHODS: We evaluated a multiyear prospective cohort study of African American children...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Open in PubMed Open full text

Identifiers

PMID: 24184149
DOI: 10.1016/j.jaci.2013.09.015
PMCID: PMC3943564

Genes

FLG2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Filaggrin-2 variation is associated with more persistent atopic dermatitis in African American subjects.PMID 24184149Read ↗

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