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Rac1 Regulates Endometrial Secretory Function to Control Placental Development

25 Aug 2015

Abstract excerpt

During placenta development, a succession of complex molecular and cellular interactions between the maternal endometrium and the developing embryo ensures reproductive success. The precise mechanisms regulating this maternal-fetal crosstalk remain unknown. Our study revealed that the expression of Rac1, a member of the Rho family of GTPases, is markedly elevated in mouse decidua on days 7 and 8 of gestation. To...

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PMID: 26305333
DOI: 10.1371/journal.pgen.1005458

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