Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BMPR2 is required for postimplantation uterine function and pregnancy maintenance

7 May 2013

Abstract excerpt

Abnormalities in cell-cell communication and growth factor signaling pathways can lead to defects in maternal-fetal interactions during pregnancy, including immunologic rejection of the fetal/placental unit. In this study, we discovered that bone morphogenetic protein receptor type 2 (BMPR2) is essential for postimplantation physiology and fertility. Despite normal implantation and early placental/fetal...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Endometriosis Research and Treatment
Share to Pregnancy and preeclampsia studies
Share to Reproductive System and Pregnancy

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 23676498
DOI: 10.1172/jci65710

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 23 Oct 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BMPR2 is required for postimplantation uterine function and pregnancy maintenancePMID 23676498Read ↗

Runx1 regulates critical factors that control uterine angiogenesis and trophoblast differentiation during placental developmentSemantic proximity Read ↗

Runx1 regulates critical factors that control uterine angiogenesis and trophoblast differentiation during placental developmentSemantic proximity Read ↗

Activin-Like Kinase 2 Functions in Peri-implantation Uterine Signaling in Mice and HumansSemantic proximity Read ↗

Bmp2 Is Critical for the Murine Uterine Decidual ResponseSemantic proximity Read ↗

Dysregulated BMP2 in the Placenta May Contribute to Early-Onset Preeclampsia by Regulating Human Trophoblast Expression of Extracellular Matrix and Adhesion MoleculesSemantic proximity Read ↗

BMP4 in Human Endometrial Stromal Cells Can Affect Decidualization by Regulating FOXO1 ExpressionSemantic proximity Read ↗

Endometrial BMP2 Deficiency Impairs ITGB3-Mediated Trophoblast Invasion in Women With Repeated Implantation FailureSemantic proximity Read ↗

Clinical significance linked to functional defects in bone morphogenetic protein type 2 receptor, BMPR2.Semantic proximity Read ↗

The Interplay of Molecular Factors and Morphology in Human Placental Development and ImplantationSemantic proximity Read ↗

Uterine stromal but not epithelial PTGS2 is critical for murine pregnancy successSemantic proximity Read ↗

Maternal IL-11Ralpha function is required for normal decidua and fetoplacental development in mice.Semantic proximity Read ↗

Integral Roles of the TGFβ Signaling Pathway in Uterine Function and DiseaseSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.