Article
The depletion of MARVELD1 leads to murine placenta accreta via integrin β4-dependent trophoblast cell invasion.
Journal of cellular physiology - 1 Mar 2018
Chen Yue, Zhang Hui, Han Fang, Yue Lei, Qiao Chunxiao, Zhang Yao, Dou Peng, Liu Weizhe, Li Yu
Abstract excerpt
The placenta is a remarkable organ, it serves as the interface between the mother and the fetus. Proper invasion of trophoblast cells is required for a successful pregnancy. Previous studies have found that the adhesion molecule integrin β4 plays important roles during trophoblast cell invasion. Here, we found that the overall birth rate of the MARVELD1 knockout mouse is much lower than that of the wild-type...
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