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Article

Decreased epithelial progesterone receptor A at the window of receptivity is required for preparation of the endometrium for embryo attachment.

Biology of reproduction - 1 Feb 2017

Wetendorf Margeaux, Wu San-Pin, Wang Xiaoqiu, Creighton Chad J, Wang Tianyuan, Lanz Rainer B, Blok Leen, Tsai Sophia Y, Tsai Ming-Jer, Lydon John P, DeMayo Francesco J

Abstract excerpt

The precise timing of progesterone signaling through its cognate receptor, the progesterone receptor (PGR), is critical for the establishment and maintenance of pregnancy. Loss of PGR expression in the murine uterine epithelium during the preimplantation period is a marker for uterine receptivity and embryo attachment. We hypothesized that the decrease in progesterone receptor A (PGRA) expression is necessary for...

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Source

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Identifiers

PMID: 28203817
DOI: 10.1095/biolreprod.116.144410
PMCID: PMC6225975

Genes

PGR
LIF
LIFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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