Article
Myostatin dysfunction is associated with reduction in overload induced hypertrophy of soleus muscle in mice.
Scandinavian journal of medicine & science in sports - 1 Aug 2016
Minderis P, Kilikevicius A, Baltusnikas J, Alhindi Y, Venckunas T, Bunger L, Lionikas A, Ratkevicius A
Abstract excerpt
The aim of the study was to investigate if myostatin dysfunction would promote the gain in muscle mass and peak isometric force (P0 ) of soleus muscle (SOL) in response to functional overloading (FO) after ablation of the gastrocnemius muscle. Fifteen male Berlin high (BEH) mice homozygous for the compact mutation causing dysfunction of myostatin and 17 mice with the corresponding wild-type allele (BEH+/+) were...
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