Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The compact mutation of myostatin causes a glycolytic shift in the phenotype of fast skeletal muscles.

The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society - 1 Dec 2013

Baán Júlia Aliz, Kocsis Tamás, Keller-Pintér Anikó, Müller Géza, Zádor Ernö, Dux László, Mendler Luca

Abstract excerpt

Myostatin is an important negative regulator of skeletal muscle growth. The hypermuscular Compact (Cmpt) mice carry a 12-bp natural mutation in the myostatin propeptide, with additional modifier genes being responsible for the phenotype. Muscle cellularity of the fast-type tibialis anterior (TA) and extensor digitorum longus (EDL) as well as the mixed-type soleus (SOL) muscles of Cmpt and wild-type mice was...

Topics

Join the communities discussing this publication.

Glycolysis
Mice
Mice, Inbred BALB C
Mice, Knockout
Muscle Fibers, Fast-Twitch

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 23979839
DOI: 10.1369/0022155413503661
PMCID: PMC3840741

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The compact mutation of myostatin causes a glycolytic shift in the phenotype of fast skeletal muscles.PMID 23979839Read ↗

Myostatin propeptide mutation of the hypermuscular Compact mice decreases the formation of myostatin and improves insulin sensitivity.Semantic proximity Read ↗

Effects of the compact mutant myostatin allele Mstn (Cmpt-dl1Abc) introgressed into a high growth mouse line on skeletal muscle cellularity.Semantic proximity Read ↗

Lack of myostatin results in excessive muscle growth but impaired force generationSemantic proximity Read ↗

Myostatin is a key mediator between energy metabolism and endurance capacity of skeletal muscle.Semantic proximity Read ↗

A deletion in the myostatin gene causes the compact ( Cmpt ) hypermuscular mutation in miceSemantic proximity Read ↗

Myostatin dysfunction is associated with reduction in overload induced hypertrophy of soleus muscle in mice.Semantic proximity Read ↗

Metabolic Functions of Myostatin and GDF11Semantic proximity Read ↗

Myostatin's marvels: From muscle regulator to diverse implications in health and diseaseSemantic proximity Read ↗

Myostatin regulation of muscle development: molecular basis, natural mutations, physiopathological aspects.Semantic proximity Read ↗

Myostatin knockout mice increase oxidative muscle phenotype as an adaptive response to exercise.Semantic proximity Read ↗

Marker-assisted introgression of the Compact mutant myostatin allele MstnCmpt-dl1Abc into a mouse line with extreme growth effects on body composition and muscularity.Semantic proximity Read ↗

Exercise training attenuates the hypermuscular phenotype and restores skeletal muscle function in the myostatin null mouse.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.