Article
Biosynthesis and uptake of siderophores is controlled by the PacC-mediated ambient-pH Regulatory system in Aspergillus nidulans.
Eukaryotic cell - 1 Apr 2004
Eisendle Martin, Oberegger Harald, Buttinger Rudolf, Illmer Paul, Haas Hubertus
Abstract excerpt
Biosynthesis and uptake of siderophores in Aspergillus nidulans are regulated not only by iron availability but also by ambient pH: expression of this high-affinity iron uptake system is elevated by an increase in the ambient pH. Mediation of this regulation by the transcriptional regulator PacC has been confirmed via acidity- and alkalinity-mimicking mutants.
Topics
- Aspergillus nidulans
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Hydrogen-Ion Concentration
- Iron
- Mutation
- Siderophores
- Transcription Factors