Article
The interleukin-1β-511 T>C (rs16944) gene polymorphism is associated with risk of developing silent myocardial ischemia in diabetic patients.
Immunology letters - 1 Nov 2015
Vargas-Alarcón Gilberto, Cruz-López Miguel, Valladares Adán, Álvarez-León Edith, Juárez-Cedillo Teresa, Pérez-Méndez Óscar, de-la-Peña Jorge Escobedo, Escobedo Galileo, Fragoso Jose Manuel
Abstract excerpt
Silent myocardial ischemia (SMI) is a multifactorial and polygenic disorder that results from an excessive inflammatory response. Considering the prominent role of IL-1β, IL-1F10 and IL-1RN as regulators of the inflammatory process and vascular physiology, the aim of the present study was to analyze whether IL-1β, IL-1F10 and IL-1RN single nucleotide polymorphisms (SNPs) are associated with SMI. One polymorphism...
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