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Article

Biochemical and molecular study on interleukin-1β gene expression and relation of single nucleotide polymorphism in promoter region with Type 2 diabetes mellitus.

Journal of cellular biochemistry - 1 Jul 2018

Tayel Safaa I, Fouda Eman A M, Elshayeb Elsayed I, Eldakamawy Asmaa R A, El-Kousy Salah M

Abstract excerpt

Interleukin-1β (IL-1β) assumes a centric role in the regulation of immune and inflammatory responses and thus has been recognized in immune mediated diseases like type 2 diabetes mellitus (T2DM). We aimed to investigate expressed level of IL-1β and its relation with IL-1β -511T>C polymorphism in T2DM patients. This study enrolled 80 subjects (50 patients with T2DM and 30 healthy control subjects). Laboratory...

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Case-Control Studies
Diabetes Mellitus, Type 2
Gene Expression Regulation
Interleukin-1beta
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Promoter Regions, Genetic

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PMID: 29323730
DOI: 10.1002/jcb.26667

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