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Article

Association of variation in the interleukin-1 gene family with diabetes and glucose homeostasis.

The Journal of clinical endocrinology and metabolism - 1 Nov 2009

Luotola Kari, Pääkkönen Rauni, Alanne Mervi, Lanki Timo, Moilanen Leena, Surakka Ida, Pietilä Arto, Kähönen Mika, Nieminen Markku S, Kesäniemi Y Antero, Peters Annette, Jula Antti, Perola Markus, Salomaa Veikko

Abstract excerpt

OBJECTIVE: Proinflammatory cytokine IL-1beta is capable of decreasing insulin-induced glucose transport. Therefore, we hypothesized that genetic variation in the IL-1 gene family is associated with measures of glucose homeostasis and diabetes. DESIGN AND OUTCOME MEASURES: Fifteen haplotype-tagging single-nucleotide polymorphisms in the IL-1alpha, IL-1beta, and IL-1 receptor antagonist genes were determined in a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 19820020
DOI: 10.1210/jc.2009-0666

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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