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Article

Association of IL1B polymorphism with left ventricular systolic dysfunction: a relation with the release of interleukin-1β in stress condition.

Pharmacogenetics and genomics - 1 Sept 2011

Guéant-Rodriguez Rosa-Maria, Juillière Yves, Battaglia-Hsu Shyue-Fang, Debard Renée, Gérard Philippe, Reyes Pedro, Danchin Nicolas, Guéant Jean-Louis

Abstract excerpt

OBJECTIVE: Proinflammatory cytokines play a major role in the pathomechanisms of heart failure. Besides this, the influence of mental stress on heart failure is poorly documented despite its effects on sympathetic stimulation of interleukin-1β (IL-1β) secretion. We examined whether the polymorphisms of proinflammatory cytokines are predictors of left ventricular systolic dysfunction (LVSD) and if so, whether such...

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Source

Identifiers

PMID: 21811191
DOI: 10.1097/FPC.0b013e3283493a05

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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