The TGF-B1 and IL-10 gene polymorphisms are associated with risk of developing silent myocardial ischemia in the diabetic patients.

doi:10.1016/j.imlet.2013.09.007

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Article

The TGF-B1 and IL-10 gene polymorphisms are associated with risk of developing silent myocardial ischemia in the diabetic patients.

Immunology letters - 1 Jan 2000

Cruz Miguel, Fragoso José Manuel, Alvarez-León Edith, Escobedo-de-la-Peña Jorge, Valladares Adan, Juárez-Cedillo Teresa, Pérez-Méndez Oscar, Vargas-Alarcón Gilberto

Abstract excerpt

Silent myocardial ischemia (SMI) is a multifactorial and polygenic disorder that results from an excessive inflammatory response. Considering the prominent role of IL-10 and TGF-B1 as regulators of the inflammatory process and vascular physiology, the aim of the present study was to analyze whether IL-10 and TGF-B1 single nucleotide polymorphisms (SNPs) are associated with SMI. The IL-10-1082 A>G (rs1800896),...

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PMID: 24060592
DOI: 10.1016/j.imlet.2013.09.007

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