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PA-X is a virulence factor in avian H9N2 influenza virus

9 Jul 2015

Abstract excerpt

H9N2 influenza viruses have been circulating worldwide in multiple avian species, and regularly infect pigs and humans. Recently, a novel protein, PA-X, produced from the PA gene by ribosomal frameshifting, was demonstrated to be an antivirulence factor in pandemic 2009 H1N1, highly pathogenic avian H5N1 and 1918 H1N1 viruses. However, a similar role of PA-X in the prevalent H9N2 avian influenza viruses has not...

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PMID: 26296365
DOI: 10.1099/jgv.0.000232

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