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Article

Impacts of different expressions of PA-X protein on 2009 pandemic H1N1 virus replication, pathogenicity and host immune responses.

Virology - 1 Apr 2017

Lee Jinhwa, Yu Hai, Li Yonghai, Ma Jingjiao, Lang Yuekun, Duff Michael, Henningson Jamie, Liu Qinfang, Li Yuhao, Nagy Abdou, Bawa Bhupinder, Li Zejun, Tong Guangzhi, Richt Juergen A, Ma Wenjun

Abstract excerpt

Although several studies have investigated the functions of influenza PA-X, the impact of different expressions of PA-X protein including full-length, truncated or PA-X deficient forms on virus replication, pathogenicity and host response remains unclear. Herein, we generated two mutated viruses expressing a full-length or deficient PA-X protein based on the A/California/04/2009 (H1N1) virus that expresses a...

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Identifiers

PMID: 28142079
DOI: 10.1016/j.virol.2017.01.015
PMCID: PMC5651993

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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