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Article

PA-X protein decreases replication and pathogenicity of swine influenza virus in cultured cells and mouse models.

Veterinary microbiology - 1 Jun 2017

Gong Xiao-Qian, Sun Ying-Feng, Ruan Bao-Yang, Liu Xiao-Min, Wang Qi, Yang Hai-Ming, Wang Shuai-Yong, Zhang Peng, Wang Xiu-Hui, Shan Tong-Ling, Tong Wu, Zhou Yan-Jun, Li Guo-Xin, Zheng Hao, Tong Guang-Zhi, Yu Hai

Abstract excerpt

Swine influenza viruses have been circulating in pigs throughout world and might be potential threats to human health. PA-X protein is a newly discovered protein produced from the PA gene by ribosomal frameshifting and the effects of PA-X on the 1918 H1N1, the pandemic 2009 H1N1, the highly pathogenic avian H5N1 and the avian H9N2 influenza viruses have been reported. However, the role of PA-X in the pathogenesis...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28622865
DOI: 10.1016/j.vetmic.2017.05.004

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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