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Article

Evolution and function of the HCV NS3 protease in patients with acute hepatitis C and HIV coinfection.

Virology - 1 Nov 2015

Dietz Julia, Lutz Thomas, Knecht Gaby, Gute Peter, Berkowski Caterina, Lange Christian Markus, Khaykin Pavel, Stephan Christoph, Brodt Hans-Reinhard, Herrmann Eva, Zeuzem Stefan, Sarrazin Christoph

Abstract excerpt

Little is known about the importance of the hepatitis C virus (HCV) NS3 protease in acute hepatitis C. In this prospective study, 82 consecutive patients with acute hepatitis C and human immunodeficiency virus (HIV) coinfection were enrolled. Individuals were infected with highly related HCV strains and the baseline NS3 quasispecies diversity and complexity was higher compared to a chronic hepatitis C control...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26295281
DOI: 10.1016/j.virol.2015.06.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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