Article

Impaired miRNA degradation by post-transcriptional addition of 3’ cytosine and adenine in T cell activation

2020-08-20

Abstract excerpt

<h4>ABSTRACT</h4> MiRNA repertoire of T cells undergoes extensive changes in response to activation. Whereas global miRNA downregulation occurs few hours after activation, some individual miRNAs are specifically up- or down-regulated. In this study, we have assessed miRNA expression and post-transcriptional modification kinetics in human primary CD4+ T cells upon short-term stimulation with αCD3αCD28 or IFN I usi...

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Literature Corpus work: be9a8baa-e4f1-5b48-b532-7f692b52099f
DOI: 10.1101/2020.08.19.257816

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