Article
MiR-568 inhibits the activation and function of CD4⁺ T cells and Treg cells by targeting NFAT5.
International immunology - 1 May 2014
Li Wei, Kong Ling-bo, Li Jun-Tang, Guo Zhang-Yan, Xue Qian, Yang Tao, Meng Yan-Ling, Jin Bo-Quan, Wen Wei-Hong, Yang An-Gang
Abstract excerpt
CD4(+) T cells play critical roles in orchestrating adaptive immune responses. Their activation and proliferation are critical steps that occur before they execute their biological functions. Despite the important role of this process, the underlying molecular events are not fully understood. MicroRNAs (miRNAs) have been shown to play important roles in lymphocyte development and function. However, the miRNAs...
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