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Article

Pharmacogenetics of alcohol and alcohol dependence treatment.

Current pharmaceutical design - 1 Jan 2010

Kranzler Henry R, Edenberg Howard J

Abstract excerpt

In this article, we review studies of genetic moderators of the response to medications to treat alcohol dependence, the acute response to alcohol, and the response to the psychotherapeutic treatment of heavy drinking. We consider four neurotransmitter systems: opioidergic, dopaminergic, GABAergic, and glutamatergic and focus on one receptor protein in each: OPRM1 (the &#micro;-opioid receptor gene), DRD4 (the...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Polymorphism, Genetic

Share to Receptors, Dopamine D4

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Source

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Identifiers

PMID: 20482509
DOI: 10.2174/138161210791516387
PMCID: PMC4142701

Genes

DRD4
GABRA2
OPRM1
GRIK1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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