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Article

Pathway based analysis of genotypes in relation to alcohol dependence.

The pharmacogenomics journal - 1 Aug 2012

Reimers M A, Riley B P, Kalsi G, Kertes D A, Kendler K S

Abstract excerpt

We introduce a method for detecting variants in several genes of related function with small effect on a phenotype of interest. Our method uses logistic regression to test whether multiple alleles within a functional set have significantly higher than expected predictive value, even though none individually may have strong individual effects. We illustrate this method by testing seven gene sets (including 48...

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Identifiers

PMID: 21468025
DOI: 10.1038/tpj.2011.10
PMCID: PMC3134610

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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