Article
Pathway based analysis of genotypes in relation to alcohol dependence.
The pharmacogenomics journal - 1 Aug 2012
Reimers M A, Riley B P, Kalsi G, Kertes D A, Kendler K S
Abstract excerpt
We introduce a method for detecting variants in several genes of related function with small effect on a phenotype of interest. Our method uses logistic regression to test whether multiple alleles within a functional set have significantly higher than expected predictive value, even though none i...
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