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Article

Myeloid Cells and Related Chronic Inflammatory Factors as Novel Predictive Markers in Melanoma Treatment with Ipilimumab.

Clinical cancer research : an official journal of the American Association for Cancer Research - 15 Dec 2015

Gebhardt Christoffer, Sevko Alexandra, Jiang Huanhuan, Lichtenberger Ramtin, Reith Maike, Tarnanidis Kathrin, Holland-Letz Tim, Umansky Ludmila, Beckhove Philipp, Sucker Antje, Schadendorf Dirk, Utikal Jochen, Umansky Viktor

Abstract excerpt

PURPOSE: Immunotherapy with ipilimumab improves the survival of patients with metastatic melanoma. Because only around 20% of patients experience long-term benefit, reliable markers are needed to predict a clinical response. Therefore, we sought to determine if some myeloid cells and related inflammatory mediators could serve as predictive factors for the patients' response to ipilimumab. EXPERIMENTAL DESIGN: We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26289067
DOI: 10.1158/1078-0432.CCR-15-0676

Genes

HMGB1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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