Article

Peripheral monocyte transcriptomics associated with immune checkpoint blockade outcomes in metastatic melanoma

2024-01-25

Abstract excerpt

<h4>ABSTRACT</h4> Clinical responses to immune checkpoint blockade (ICB) for metastatic melanoma (MM) are variable, with patients frequently developing immune related adverse events (irAEs). The role played by myeloid populations in modulating responses to ICB remains poorly defined. We explored the effect of MM and the response to ICB across a cohort of patients with MM (n=116) and healthy donors (n=45) using bul...

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Literature Corpus work: e0ae2a5b-6237-5c7a-8dd5-3ede91e459a1
DOI: 10.1101/2024.01.25.24301653

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