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Article

High expression of ID1 in monocytes is strongly associated with phenotypic and functional MDSC markers in advanced melanoma.

Cancer immunology, immunotherapy : CII - 1 Apr 2020

Melief Jeroen, Pico de Coaña Yago, Maas Roeltje, Fennemann Felix-Lennart, Wolodarski Maria, Hansson Johan, Kiessling Rolf

Abstract excerpt

The efficacy of immunotherapies for malignant melanoma is severely hampered by local and systemic immunosuppression mediated by myeloid-derived suppressor cells (MDSC). Inhibitor of differentiation 1 (ID1) is a transcriptional regulator that was shown to be centrally involved in the induction of immunosuppressive properties in myeloid cells in mice, while it was overexpressed in CD11b+ cells in the blood of...

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Identifiers

PMID: 31953577
DOI: 10.1007/s00262-019-02476-9
PMCID: PMC7113206

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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