ABCB1 and ABCC1 variants associated with virological failure of first-line protease inhibitors antiretroviral regimens in Northeast Brazil patients.

doi:10.1002/jcph.165

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Article

ABCB1 and ABCC1 variants associated with virological failure of first-line protease inhibitors antiretroviral regimens in Northeast Brazil patients.

Journal of clinical pharmacology - 1 Dec 2013

Coelho Antonio V C, Silva Suedja P S, de Alencar Luiz C A, Stocco Gabriele, Crovella Sergio, Brandão Lucas A C, Guimarães Rafael L

Abstract excerpt

The present study aims at evaluating the association between seven single nucleotide polymorphisms (SNPs) in five genes involved on antiretroviral pharmacokinetic pathways and virological failure in first line highly active antiretroviral therapy. Seven candidate polymorphisms (rs3842 and rs10456...

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Identifiers

PMID: 23996099
DOI: 10.1002/jcph.165

Genes

ABCB1
ABCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-23996099-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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