Article
Effect of genotype and methylation of CYP2D6 on smoking behaviour.
Pharmacogenetics and genomics - 1 Nov 2015
Tiili Emmi M, Antikainen Miia S H, Mitiushkina Natalia V, Sukhovskaya Olga A, Imyanitov Evgeny N, Hirvonen Ari P
Abstract excerpt
OBJECTIVE: Cigarette smoking is one of the most influential environmental factors affecting the DNA methylation patterns. The addiction-causing substance of tobacco smoke, nicotine, has also shown the potential to alter DNA methylation patterns. However, genetics has a strong influence on DNA methylation patterns, which in turn may affect an individual's smoking behaviour. MATERIALS AND METHODS: We studied eight...
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