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Article

The genotypes and methylation of MAO genes as factors behind smoking behavior.

Pharmacogenetics and genomics - 1 Nov 2017

Tiili Emmi M, Mitiushkina Natalia V, Sukhovskaya Olga A, Imyanitov Evgeny N, Hirvonen Ari P

Abstract excerpt

OBJECTIVE: Smoking dependence is the main cause for tobacco-related illnesses. The addiction-causing substance in tobacco, nicotine, acts through the dopamine pathway in the brain, causing several pleasurable experiences through cigarette smoking. Thus, both genetic and epigenetic factors related to dopamine metabolism may play an important role in influencing an individual's smoking behavior. MATERIALS AND...

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Source

Identifiers

PMID: 28858992
DOI: 10.1097/FPC.0000000000000304

Genes

MAOA
MAOB

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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