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Article

Disruption of eyelid and cornea morphogenesis by epithelial β-catenin gain-of-function.

Molecular vision - 1 Jan 2015

Mizoguchi Shin, Suzuki Kentaro, Zhang Jianhua, Yamanaka Osamu, Liu Chia-Yang, Okada Yuka, Miyajima Masayasu, Kokado Masahide, Kao Winston W Y, Yamada Gen, Saika Shizuya

Abstract excerpt

PURPOSE: To examine the developmental pathobiology of the eyelid and the cornea caused by epithelial β-catenin gain-of-function (gof) during mouse embryogenesis. METHODS: Compound mutant mice (Ctnnb1(GOFOSE) , gof of β-catenin in the epidermis and the ocular surface epithelium) were generated by time-mating keratin 5-promoter-Cre recombinase (Krt5-Cre) and Ctnnb1(fE3/WT) (floxed exon 3 of Ctnnb1) mice. Eyes...

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PMID: 26283861
PMCID: PMC4522241

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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