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Article

The signaling pathways in tissue morphogenesis: a lesson from mice with eye-open at birth phenotype.

Biochemical pharmacology - 15 Sept 2004

Xia Ying, Kao Winston W-Y

Abstract excerpt

Tissue morphogenesis during development is regulated by growth factors and cytokines, and is characterized by constant remodeling of extracellular matrix in response to signaling molecules. MEK kinase 1 (MEKK1) is a mitogen-activated protein kinase (MAPK) kinase kinase originally identified as an upstream activator for several MAPK pathways. During mouse embryogenesis, MEKK1 controls cell shape changes and...

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Identifiers

PMID: 15313393
DOI: 10.1016/j.bcp.2004.05.028

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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